“Astounding” new evidence suggests ‘party drug’ Ketamine can cure/end depression in the elderly.
Australian researchers at the Black Dog Institute completed the world’s first randomized control trial (RCT), assessing the efficacy and safety of ketamine as a treatment for depression in elderly patients.
A total of 16 patients over the age of 60, many of whom had suffered from depression for years and found other treatments ineffective, were given low doses of the drug.
Increasing doses of ketamine were given over a period of five weeks, with doses tailored for each individual participant.
The results, published in the latest American Journal of Geriatric Psychiatry, provide preliminary evidence that ketamine is effective as an antidepressant – when delivered in repeated intravenous doses.
“What we noticed was that ketamine worked incredibly quickly and incredibly effectively,” Professor Colleen Loo, who led the pilot program told ABC News. “By incredibly effective, we mean going rapidly from severely depressed to being completely well in one day.”
“Some people think, ‘oh maybe it was just a drug induced temporary high’ — and it wasn’t,” she said. “You had the woozy effects in the first hour or so, but the antidepressant effects kicked in later.”
While the illicit narcotic has a reputation as a rave drug, it has long been used as an anaesthetic or sedative. None of the participants experienced problematic side effects, according to the research team who administered the drug through a small injection under the skin.
“Our results indicate a dose-titration method may be particularly useful for older patients, as the best dose was selected for each individual person to maximize ketamine’s benefits while minimizing its adverse side effects,” she said.
Further study is needed, however, to understand the risks of ketamine use and possible side effects, such as its impact on liver function.
The institute will continue its research with a much larger, three-year trial into the drug’s efficacy as a treatment for major depression.
The trial, which aims to be the world’s largest in this field, will be made up of 200 Australian and New Zealand participants who have not responded to existing medications for major depression.
Dementia, which is caused by physical changes in the brain, leads to memory loss and hampers other mental abilities.
Nine ways to reduce dementia
1. Maintain good hearing
2. Complete secondary education
3. Stop smoking
4. Reduce depression
6. Social activity
7. Treat high blood pressure
8. Healthy weight
9. Treat Type 2 diabetes
“Our results suggest that around 35 percent of dementia is attributable to a combination of the following nine risk factors: education to a maximum of age 11-12 years, mid-life hypertension, mid-life obesity, hearing loss, late-life depression, diabetes, physical inactivity, smoking, and social isolation,” the study said.
Researchers found if people stayed in school until the age of 15, the benefits of education and socialisation would help reduce the cases of dementia by eight percent.
“Although dementia is diagnosed in later life, the brain changes usually begin to develop years before,” said lead author Professor Gill Livingston, from University College London.
“Acting now will vastly improve life for people with dementia and their families and, in doing so, will transform the future of society.”
The researchers said maintaining good hearing between the ages of 45 and 65 reduces the number of cases by nine percent.
Quitting smoking could reduce the number of cases by five percent, it said.
Other factors contributing to the risk include depression (four percent), physical inactivity (three percent), social isolation (two percent), high blood pressure (two percent), obesity (one percent) and type 2 diabetes (one percent).
The study said the global cost of dementia in 2015 was estimated to be $818bn, and that this figure would continue to rise.
It said nearly 85 percent of these costs were “related to family and social, rather than medical, care”.
The researchers noted, however, that the study was limited.
“We have not incorporated other potential risk factors, such as diet, alcohol, living near major roads, or sleep, which could be relevant,” it said. “Therefore, the potentially preventable fraction of dementia might be underestimated in our figures.”
(Natural News) When people are faced with a serious ailment, their tendency is to go to a hospital and have themselves checked by a general practitioner. They then take the medication prescribed by the doctor and hope everything will be alright. These people, on the other hand, took a different direction when it came to searching for a cure.
Meet 45-year-old Suffolk, England hotel manager Nicole Green, who had been diagnosed in 2008 with multiple sclerosis (MS), a neurological disease that is characterized by vision impairment and a loss of motor control. She reportedly cured herself with a diet of flax seeds and fish. Then there‘s 52-year-old West Wycombe retired civil servant Bill Rogers, who, instead of taking statins to regulate his cholesterol levels, turned to food such as sweet potatoes, chickpeas, and soya.
This seems to suggest that having proper diet is as effective – perhaps even more – as ingesting commercial drugs when it comes to curbing the effects of a disorder or disease, or neutralizing a condition that can make your health take a turn for the worse.
A study that was recently conducted by Professor Giovanni de Gaetano of the Neuromed Institute in Pozzini, Italy concluded that people who were suffering from heart ailments who had a habit of eating vegetables, fish, nuts, and olive oil lessened their chances of dying a premature death by 37 percent. These are greater odds than those who take statins; their chances of dying a premature death were only lessened by 18 percent.
Physicians all over the world, however, are not aware of these findings and still believe in the power of medicine as the best way to cure ailments. In an urgent call to the Medical Schools Council and the General Medical Council to shed light on this matter, Dr. Aseem Malhotra, a consultant cardiologist at the Lister Hospital in Stevenage in Hertfordshire, said, “There is little or no training at medical school or postgraduate level of the impact of nutrition on health.”
Nevertheless, some doctors are acknowledging the effect nutrition can have on health. For instance, University of Melbourne neuroepidemiologist Professor George Jelinek invested in a plant-based wholefood diet of seafood (for 20 milliliters to 30 ml or omega-3 fatty acids per day) and flax seed oil (for vitamin D) to cure his MS after he was diagnosed with it 18 years ago.
Another diet, this one for treating irritable bowel syndrome (IBS), was conceptualized in 2012 by scientists at Monash University in Melbourne, Australia. The scientists advised patients with IBS to cut back on their intake of foods rich in fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAP), which can be found in wheat products; fruits and vegetables such as celery, pears, peaches, leeks, apples, cabbage, onions, and plums; garlic; and dairy.
Twenty-nine-year-old Camberley, Surrey administrator Hannah Crossland-Scott, who had been suffering from IBS since she was 14, tried this diet. “The diet was terribly restrictive, but it was astonishing – within a week I’d noticed improvements and now I rarely get a flare-up if I avoid my trigger foods, such as dairy, onions, garlic, and melon, or anything with gluten.”
People with high cholesterol levels are told to lessen their fat and red meat intake and follow a Mediterranean diet. An alternative to this is the diet that was developed by nutritionist Ian Marber and Dr. Laura Corr, a cardiologist at Guy’s and St. Thomas’ NHS Foundation Trust, which is composed of the ample intake of healthy oils such as olive oil, fiber, nuts, oats, soya, and foods that are rich in plant sterols, which are good for absorbing cholesterol into the body from the gut.
Speaking for the diet, Bristol Heart Institute interventional consultant cardiologist Dr. Julian Strange said: “We don’t have a huge amount of evidence that diets like this will make you live longer – unlike statins where there is hard evidence that they can reduce heart attack or stroke. But the diet may help you lower cholesterol.”
This kind of thinking – that food is a better cure than medication – is not new, and has already surfaced across the pond four years ago. Philadelphia, Pennsylvania-based Metropolitan Area Neighborhood Nutrition Alliance (MANNA) in 2013 commissioned a study that made them believe that proper nutrition contributed to a better quality of life in the long-term. As such, they incorporated specific meal plans for different kinds of patients, and over the course of a year their diabetic clients saw their medical expenses decreasing by $12,000 per month.
“We get dramatic results because we care for the sickest clients. The potential for savings is much greater for these people,” MANNA’s director of policy and institutional affairs Ann Hoskins-Brown said.
(Natural News) More than 350 million people on our planet suffer from depression, and it also has a profound effect on their loved ones. One of the most popular treatments, SSRI antidepressants, is risky, expensive, and not terribly effective. This has prompted some scientists to look for alternatives, and it appears they may have found a good solution in the form of magnesium.
This mineral is vital for many of our body’s functions, including our blood pressure, heart rhythm and bone strength. It also helps fight inflammation in the body. Now, scientists from the University of Vermont’s Larner College of Medicine have found promising results after a clinical trial involving the use of over-the-counter magnesium tablets in depressed patients.
In the blocked and randomized crossover trial of 126 adults using outpatient primary care clinics, participants with mild to moderate depression were studied over the course of 12 weeks. Some participants were given 248 milligrams of magnesium each day for the course of six weeks followed by six weeks without it, whereas those in the control group received no treatment for six weeks followed by six weeks of magnesium. All participants were given biweekly assessments of their depression symptoms.
Those who took the elemental magnesium chloride noted clinically significant improvements in anxiety symptoms and measures of depression. On the Patient Health Questionnaire 9, which asks patients nine questions to diagnose and then classify depression, participants scored six points lower on average during their time taking magnesium.
Best of all, they experienced these improvements after just two weeks of taking the magnesium. In addition, patients of all ages and depression types tolerated the supplements well and noted similar levels of effectiveness.
Connection between magnesium and depression has already been established
This appears to support another study in a Croatian psychiatric hospital that discovered that many patients who had attempted suicide suffered from dangerously low levels of magnesium. In fact, depression can be a sign of magnesium deficiency, as can ringing in your ears, muscle cramps, kidney stones, and abnormal heart function.
More than 60 percent of the participants said they planned to use magnesium in the future to manage their depression. Life Extension reports that 68 percent of people in the U.S. are not consuming the recommended daily requirement of this vital mineral, while 19 percent don’t even manage to get half of the amount they need.
Magnesium can be found in fruits like organic oranges, bananas, pineapples, avocados and cherries. You’ll also find it in seafood like mackerel and shrimp, yogurt, dark chocolate, legumes, leafy greens, spirulina and chlorella.
Further research needed
Next, the researchers would like to see if they can get the same results using an even bigger and more diverse population. It is hoped that magnesium and other safe alternatives could eventually replace antidepressants entirely, given their extremely dangerous side effects like seizures, suicidal behavior, and other serious health problems.
It’s hard to imagine why anyone would want to take these dangerous drugs when there are safer choices. Of course, Big Pharma will do their best to make sure the public doesn’t hear about alternatives, with the global market for these drugs expected to exceed $13 billion by the year 2018.
Depression is a serious condition and it’s perfectly understandable for sufferers and those around them to want to find a way to control it, but many who take SSRIs and live to tell the tale regret it. Thankfully, it looks like magnesium can be added to other natural forms of relief like yoga, meditation, exercise, and vitamin D. Why turn to drugs when you can give your body what it needs to heal itself?
Not only is turmeric anti-inflammatory and an anti-coagulant, studies have shown it benefits arthritis, cancer, heartburn, and depression.
Feeling down? Before you reach for a prescription drug to help remedy your depression, consider making this anti-inflammatory turmeric drink that is side effect-free and tastes delicious.
In case you didn’t know, turmeric is incredibly medicinal. Research has shown that not only is the root an anticoagulant (slows and prevents blood clotting) and an anti-inflammatory, it aids cancer treatment and is an anti-depressant, due to curcumin which studies have shown is more effective than fluoxetine which Prozac contains. Research has also concluded that turmeric can benefit conditions such as skin cancer, Alzheimer’s, arthritis, heartburn, jaundice, diarrhea, and gallbladder and stomach pain.
Fortunately, it’s easier than ever to take advantage of Mother Nature’s cures. And, it is for this reason True Activist is sharing the following Turmeric Lemonade recipe. Set some time aside to make this medicinal drink and sip on it during the day for best results.
Credit: The Whole Journey
Preparation Time: 10 minutes
Serving Size: 3-4
4 cups cold filtered water
2 Tbsp freshly grated or powdered turmeric
5 Tbsp 100% maple syrup or raw honey
Juice of 1 1/2 lemons
Dash of cinnamon
Combine all ingredients in a pitcher and stir until well-combined.
Not only is this recipe economical to make, it is delicious and packs a powerful punch.
Brain damage is often a result of unnecessary stress and exposure to air pollutants.
You might reconsider the consequence of these seemingly innocuous habits when you learn how they can inhibit neurological function and cause the brain to age.
Remember, for the most part, your comfort zone isn’t doing you any favours. Break away from your normal routine and explore, write, create and travel. Try new things that stimulate the senses. Learning new skills keeps your brain young, and should be a priority at every age.
2. Skipping Breakfast
Not eating breakfast can lead to lower blood sugar levels, which ultimately deprives your brain of nutrients. If your brain isn’t given sufficient nutrition, it begins to degenerate. Eat a healthy, filling breakfast high in protein.
Smoking cigarettes can cause obstruction of blood flow to the brain, and also can lead to escape of blood into brain tissue. Smoking can cause brain cells to shrink, and has been linked to Alzheimer’s disease, strokes,
4. Eating Sugar
Eating sugar triggers inflammatory responses throughout the body, which ultimately stresses and ages cells. This can effect “from cognitive function to psychological wellbeing”. Sugar also has been linked to depression and anxiety.
5. Sleep Deprivation
When you’ve chronically been deprived of sleep, the brain is forced to emit stress responses which inflame and incite brain degeneration. Not sleeping naturally induces bad moods, lethargy and leads to depression and weight gain due to cortisol production. If you are in this habit currently, you may not realize it, but once you have a little sleep, you will soon notice the positive effect it has on your brain.
6. Covering Head While Sleeping
If you’re dependent on sleeping with a blanket covering your head then you might want to reconsider. The more ventilation, the better, because you want to be exposed to oxygen. Allow the body and mind to breathe in fresh air— the fresher the better. Open the windows, use fans, light incense, herbs, or aromatherapy.
When you overindulge on food, the body can become overloaded by the refined sugars and fats, and release stress responses as a result. These types of foods also clog arteries, which can lead to blockages in the brain.
8. Avoiding Change/ Not Speaking
The brain craves intellectual stimulation. Spend time with people who challenge your traditional patterns of thinking. The brain can get into ruts of small-minded thinking, which ultimately inhibit growth. This is how evolution is able to take place, by developing adaptation to our respective environments. Humans need to express themselves verbally and spend time with people who are different from themselves.
Some citifies (sic)experience more air pollution because they use wood-burning stoves or burn carbon in electricity production. You can look up the air quality index in your area, here.
10. Not resting the brain.
The brain functions like a muscle, and therefore it needs to be rested in order for exercise to be integrated. When the brain experiences the type of relaxation induced by meditation, it clears passages and triggers change on a deep level. This improves cognitive functions. Most daily actions are taking place on a superficial level, which produces a natural anxiety in most people, which is an unhealthy habit. Meditation helps inhibit this type of hyperactivity, stressful mode of the brain.
Europe is the region with the highest number of suicides in the world, according to World Health Organization (WHO). The group’s annual world health report shows that Europe’s highest suicide rate is in Lithuania, with 32.7 suicides per 100,000. The revelations come during Mental Health Awareness Month.
Lithuania, Kazakhstan, Belarus, Poland and Latvia: these are the five European nations with the highest number of suicides, with all more than 21 suicides per 100,000 people.
That’s according to a comprehensive report by the World Health Organization (WHO), on the general health of the world’s population, and on common causes of death.
“Men are almost twice as likely as women to die as a result of suicide. Suicide mortality rates are highest in the WHO European Region (14.1 per 100,000 population) and lowest in the WHO Eastern Mediterranean Region (3.8 per 100,000 population).”
In 2015, suicide was the second leading cause of death by injury after road traffic injuries. Serious depression is suggested as a significant factor in people being pushed to take their own lives, which the WHO estimates affects 311 million people worldwide.
The global health organization is calling for national governments to reduce access to pesticides and other poisons to help reduce the availability of cheap suicide methods.
“A leading means of suicide in many parts of the world is self-poisoning with pesticides.”
The impact of access to pesticides on suicide rates was first identified in a 1995 study that demonstrated both an increase in suicide mortality following the introduction of paraquat (a highly toxic herbicide) in Samoa in 1972, and a subsequent reduction in such mortality after its banning in 1981.”
The WHO report highlighted South Korea’s suicide rate falling due to a pesticide ban in 2011.
Marie-Paule Kieny, the WHO’s assistant director-general for health systems and innovation, said in a statement:
“If countries don’t know what makes people get sick and die, it’s a lot harder to know what to do about it.”
“The WHO is working with countries to strengthen health information systems and improve data quality,” she added.